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Journal of Biomaterials Applications
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Histological Assessment of Sintered Metal- Fibre-Web Materials

J.A. Jansen

Department of Oral Function Laboratory of Biomaterials Dental School University of Nijmegen P. O. Box 9101 6500 HB Nijmegen The Netherlands

M.A. Van't Hof

Department of Medical Statistics Faculty of Medical Sciences University of Nijmegen P. O. Box 9101 6500 HB Nijmegen The Netherlands

Recently it has been shown that flexible metal fibre mesh structures can be used for the subcutaneous stabilisation of percutaneous devices. However, for the safe application of fibre mesh structures, it is necessary that these materials possess certain biological properties. The purpose of this paper is to discuss surgical, statistical and histological methods for the testing and evaluation of metal fibre web materials for soft tissue application. The use and potential of the described techniques are demonstrated with two examples.

Key Words: histology • histomorphometry • fibre-web • connective tissue • implant.

Journal of Biomaterials Applications, Vol. 9, No. 1, 30-54 (1994)
DOI: 10.1177/088532829400900102
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