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Journal of Biomaterials Applications
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Hollow Fiber Hemodialyzers for Partial Respiratory Support

CH Kostopoulos

Department of Clinical Therapeutics Athens University Alexandra Hospital 2 Vas. Sofias and Lourou Str. 115-28 Athens, Greece

A. Rasidakis

Department of Clinical Therapeutics Athens University Alexandra Hospital 2 Vas. Sofias and Lourou Str. 115-28 Athens, Greece

SP Moulopoulos

Department of Clinical Therapeutics Athens University Alexandra Hospital 2 Vas. Sofias and Lourou Str. 115-28 Athens, Greece

Acute respiratory failure is still characterized by a high mortal ity rate, in spite of the development of ingenious treatment modalities involv ing mechanical ventilation and extracorporeal respiratory support. The coex istence of renal failure further complicates the outlook for respiratory failure patients.

In this paper the development of the blood oxygenator and current aspects of its application are described. The concept of applying dialysis membranes for partial respiratory support is presented. An experimental animal model which was performed with A-V cannulation using dialysis membranes for partial respiratory support and simultaneous dialysis is analyzed. It is concluded that dialysis membranes are efficient for blood gas exchange and that their use in the management of the above-mentioned types of critically ill patients is promising.

Key Words: acute respiratory failure • extracorporeal membrane oxygena tion • dialysis membranes.

Journal of Biomaterials Applications, Vol. 4, No. 2, 123-140 (1989)
DOI: 10.1177/088532828900400203
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