Advanced Search

Journal Navigation

Journal Home

Subscriptions

Archive

Contact Us

Table of Contents

Sign In to gain access to subscriptions and/or personal tools.
Journal of Biomaterials Applications
This Article
Right arrow Full Text (PDF)
Right arrow References
Right arrow Alert me when this article is cited
Right arrow Alert me if a correction is posted
Services
Right arrow Email this article to a friend
Right arrow Similar articles in this journal
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Add to Saved Citations
Right arrow Download to citation manager
Right arrowRequest Permissions
Right arrow Request Reprints
Right arrow Add to My Marked Citations
Citing Articles
Right arrow Citing Articles via Google Scholar
Right arrow Citing Articles via Scopus
Google Scholar
Right arrow Articles by Chang, T. M. S.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Chang, T. M. S.
Social Bookmarking
Add to CiteULike   Add to Complore   Add to Connotea   Add to Del.icio.us   Add to Digg   Add to Reddit   Add to Technorati   Add to Twitter  
What's this?

Artificial Cells as Bioreactive Biomaterials

Thomas Ming Swi Chang, M.D., PH.D

Artificial Cells and Organs Research Centre Faculty of Medicine McGill University 3655 Drummond Street Montreal, Quebec, PQ Canada H3G 1Y6

Artificial cells can have the same dimensions as biological cells. They can enclose and retain a large variety of bioreactants. Artificial cell membranes can have the required permeability characteristics to allow the rapid equilibration of external molecules to be acted on by the enclosed bioreactants. Polymer, protein, protein-lipid, polymer-lipid, lipid or other materials can form artificial cell membranes. It is possible to vary the membrane thickness and permeability characteristics over a wide range. Many different forms of bioreactive artificial cells are available. This article contains only a few examples. This includes its applications in (1) red blood cell substitutes; (2) immobilisation of enzymes, multienzymes with cofactor recycling, cell cultures and other biotechnological applications; (3) hemoperfusion in kidney failure, poisoning, removal of aluminium and iron; (4) use in liver failure; (5) other applications in microencapsulation.

Key Words: Artificial cells • microencapsulation • blood substitutes • hemoperfusion • immobilised enzymes • immobilised cells • artificial kidney • artificial liver • detoxification • blood purification • immunosorbent.

Journal of Biomaterials Applications, Vol. 3, No. 1, 116-125 (1988)
DOI: 10.1177/088532828800300106
Add to CiteULike CiteULike   Add to Complore Complore   Add to Connotea Connotea   Add to Del.icio.us Del.icio.us   Add to Digg Digg   Add to Reddit Reddit   Add to Technorati Technorati   Add to Twitter Twitter    What's this?