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Journal of Biomaterials Applications
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Bone Augmentation with Bioactive Glass in Three Cases of Dental Implant Placement

Antonietta M. Gatti

The National Institute of Physics of Matter, Laboratory of Biomaterials, Department of Neurosciences, University of Modena and Reggio Emilia, Via del Pozzo 71, 41100 Modena - Italy, gatti{at}unimo.it

Leopoldo A. Simonetti

The National Institute of Physics of Matter, Laboratory of Biomaterials, Department of Neurosciences, University of Modena and Reggio Emilia, Via del Pozzo 71, 41100 Modena - Italy

Emanuela Monari

The National Institute of Physics of Matter, Laboratory of Biomaterials, Department of Neurosciences, University of Modena and Reggio Emilia, Via del Pozzo 71, 41100 Modena - Italy

Stefano Guidi

The National Institute of Physics of Matter, Laboratory of Biomaterials, Department of Neurosciences, University of Modena and Reggio Emilia, Via del Pozzo 71, 41100 Modena - Italy

David Greenspan

The National Institute of Physics of Matter, Laboratory of Biomaterials, Department of Neurosciences, University of Modena and Reggio Emilia, Via del Pozzo 71, 41100 Modena - Italy

This study reports the clinical use of a bioactive bone graft material, PerioGlas®, in the treatment of dental extraction sites before dental implant placement, to effect bone regeneration and to give early fixation to the implant.

PerioGlas®, granules, ranging from 90 to 710 mm, are implanted after tooth extraction in three patients; after 6 months bone biopsies were performed in the site of the glass implantation and observed under Electron Scanning Microscopy.

All the granules showed a biodegradation involving precipitation of calcium phosphate that worked as a scaffold for osteoblasts colonization. All cases examined showed the bioactivity of PerioGlas® granules resulting in new bone formation and biodegradation of the glass. After a two-year clinical follow-up all the implants were successfully loaded and appeared stable.

Key Words: bioactive materials • implants • dentistry • bone defects

This version was published on April 1, 2006

Journal of Biomaterials Applications, Vol. 20, No. 4, 325-339 (2006)
DOI: 10.1177/0885328206054534
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