Advanced Search

Journal Navigation

Journal Home

Subscriptions

Archive

Contact Us

Table of Contents

Sign In to gain access to subscriptions and/or personal tools.
Journal of Biomaterials Applications
This Article
Right arrow Full Text (PDF)
Right arrow References
Right arrow Alert me when this article is cited
Right arrow Alert me if a correction is posted
Services
Right arrow Email this article to a friend
Right arrow Similar articles in this journal
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Add to Saved Citations
Right arrow Download to citation manager
Right arrowRequest Permissions
Right arrow Request Reprints
Right arrow Add to My Marked Citations
Citing Articles
Right arrow Citing Articles via Google Scholar
Right arrow Citing Articles via Scopus
Google Scholar
Right arrow Articles by Mohanty, M.
Right arrow Articles by Menon, K. V.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Mohanty, M.
Right arrow Articles by Menon, K. V.
Social Bookmarking
Add to CiteULike   Add to Complore   Add to Connotea   Add to Del.icio.us   Add to Digg   Add to Reddit   Add to Technorati   Add to Twitter  
What's this?

Spinal Fixation Device: A 6-Year Postimplantation Study

Mira Mohanty

Division of Implant Biology Biomedical Technology Wing Sree Chitra Tirunal Institute for Medical Sciences and Technology Thiruvananthapuram, Kerala - 695 012, India, mira{at}sctimst.ker.nic.in

Sulekha Baby

Division of Implant Biology Biomedical Technology Wing Sree Chitra Tirunal Institute for Medical Sciences and Technology Thiruvananthapuram, Kerala - 695 012, India

K. V. Menon

Department of Orthopedics Amritha Institute of Medical Sciences and Research Centre Kochi, Kerala, India

Long-term tissue response to a metal device is described here. The components of a spinal fixation device were removed 6 years after implantation, following the need for revision surgery after a fall. Scanning electron microscopy (SEM) revealed changes in surface topography of the metal. Examination of the adjacent tissue showed a chronic inflammatory response with occasional metal debris. Immunohistochemistry identified the predominant macrophages and abundant neovascularization. The presence of macrophages in tissues adjacent to the implants, in an otherwise asymptomatic person, is noteworthy.

Key Words: spinal fixation device • metal • macrophages

Journal of Biomaterials Applications, Vol. 18, No. 2, 109-121 (2003)
DOI: 10.1177/088532803034746
Add to CiteULike CiteULike   Add to Complore Complore   Add to Connotea Connotea   Add to Del.icio.us Del.icio.us   Add to Digg Digg   Add to Reddit Reddit   Add to Technorati Technorati   Add to Twitter Twitter    What's this?