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Journal of Biomaterials Applications
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Surface Modification of Titanium Based Biomaterials by Ion Beam

Liu Xianghuai

Ion Beam Laboratory, Shanghai Institute of Metallurgy, Chinese Academy of Sciences, Shanghai 200050, P. R. China

Zheng Zhihong

Ion Beam Laboratory, Shanghai Institute of Metallurgy, Chinese Academy of Sciences, Shanghai 200050, P. R. China

Zhou Zhuyao

Ion Beam Laboratory, Shanghai Institute of Metallurgy, Chinese Academy of Sciences, Shanghai 200050, P. R. China

Huang Nan

Southwestern Jiaotong University, Chengdu 610031, P. R. China

Yang Ping

Southwestern Jiaotong University, Chengdu 610031, P. R. China

Cai Guanjun

Southwestern Jiaotong University, Chengdu 610031, P. R. China

Chen Yuanru

Southwestern Jiaotong University, Chengdu 610031, P. R. China

Ion beam enhanced deposition (IBED) was adopted to synthesize biocompatible titanium oxide film. Structure characteristics of titanium oxide film were investigated by RBS, AES, and XRD. The blood compatibility of the titanium oxide film was studied by measurements of blood clotting time and platelet adhesion. The results show that the anticoagulation property of titanium oxide film is improved significantly. The mechanism of anticoagulation of the titanium oxide film was discussed.

Key Words: IBED • titanium oxide film • blood compatibility • clotting time • platelet adhesion

Journal of Biomaterials Applications, Vol. 10, No. 4, 330-337 (1996)
DOI: 10.1177/088532829601000403
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 J Biomater ApplHome page
M. F. Maitz, M.-T. Pham, E. Wieser, and I. Tsyganov
Blood Compatibility of Titanium Oxides with Various Crystal Structure and Element Doping
J Biomater Appl, April 1, 2003; 17(4): 303 - 319.
[Abstract] [PDF]